Is Biohacking Really the Future of Wellness?

When Nature Calls, a visionary space for self-optimization in the heart of Amsterdam invites us to explore their revolutionary approach to community, wellness and plant medicine. What began in 1998 as one of Amsterdam’s earliest smart shops has transformed into a refined, high-touch experience blending biohacking, plant medicine, and modern and ancient self optimization practices.

Patrick De Jongh, the founder of the space and a natural entrepreneur, shares how he saw a gap in the market and built When Nature Calls into a gorgeous space for those curious about the power of psychedelics and natural substances. Haylin, with her background in neuroscience and business, brings an evidence-based perspective to the movement, ensuring that their approach is rooted in both research and real-world experience. Together, they’ve created an environment that is both welcoming and elevated—one that invites deep personal exploration without the usual stigma.

In this episode:

  • Smart Shop to Self-Optimization Sanctuary: Patrick shares how When Nature Calls evolved beyond psychedelics into a holistic wellness destination.
  • The Power of Set & Setting: Haylin emphasizes how their intentional, design-forward space makes plant medicine approachable and transformative.
  • The Rise of Microdosing & Mental Well-being: The shift from recreational to intentional use has reshaped the industry, especially post-pandemic. Now we we are coming into a new age of a more holistic approach to wellness.
  • Bridging Business & Well-being: Both guests highlight the intersection of neuroscience, biohacking, and holistic health in their work and how that interacts with the priorities of the mission.
  • A Vision for the Future: Expanding the notion of wellness and set and setting into every day life, and not just for retreats or journeys.

When Nature Calls, wellness isn’t just about a single experience—it’s a lifestyle. Whether you’re an experienced explorer of plant medicine or simply curious about what’s possible, their space offers a trusted entry point into a deeper connection with yourself.

The Cutting Edge of Self Optimization

If you’re in Amsterdam, visit When Nature Calls to experience their beautifully designed space, join a class, or explore their curated selection of plant-based products. Learn more at WhenNatureCalls.nl.

For more on the art of intentional living, community, and personal growth, join us at HouseofPeregrine.com. Where we are often collaborating with WNC for events and more.

We are always looking for new things we can bring to our community to help you craft our life story with intention.

 

View the transcript here.